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GREYC was created in 1995 by merging the "Laboratory of Computer Science and Artificial Intelligence of Caen" (LAIAC, Université de Caen et ENSICAEN-ISMRA) and the "Laboratoire d'Electronique et d'Instrumentation" (LEI, ENSICAEN-ISMRA). He acquired double academic tutelage : ENSICAEN-ISMRA and University of Caen. Initially recognized (1995) as Associate Research Unit CNRS, he became UPRESA during the period 96-99 and UMR from 2000. The GREYC laboratory was working in the fields of computing, imaging and electronics and was organized into 4 teams, two teams, Algorithms and I3 (Information, Intelligence, Interaction) who worked on the site of University and two teams, Image and Instrumentation, working on the site ENSICAEN-ISMRA.

In January 2003, the LAP laboratory (Laboratory of Automatic Process) which had the status of Host Team was incorporated and formed a new team. This is also the date that the I3 team gave birth to three teams : Island, Dodola and MAD.

In addition, the Instrumentation team has become Electronics team.

Since its origins, the GREYC develops research in Computer Security, especially in collaborations - initiated in the late 80s, around issues of cryptography - with the mathematics laboratory LMNO and the France Telecom R & D company. Synergistically Computer Security is one of the pillars of the CPER 2007-2013 project "ICT and security" carried by the GREYC. In January 2007, the R & D DRI ENSICAEN group working in payment systems and computer security has joined the GREYC. At the end of 2008, the GREYC has created the axis "Computer Security and Uses" to promote and enhance its activities in these areas, that they relate to the protection of information, cryptography, electronic banking or biometrics, and to develop applications platforms. This combination of skills has increased the visibility of these activities already recognized in the competitiveness cluster TES (Secure Electronic Transactions).

At the end of 2010, the activities report writtenfor the AERES highlighted the development of forces of different teams and of Norman scientific landscape: in particular the emergence of a clearly identified thematic on Digital Document and the strengthening of activities in the field of Secure Electronic Transactions. Several teams (Algorithms, Dodola, Island) have been reorganized for greater consistency and visibilty: AMACC (algorithms, complexity, information protection), CODAG (data mining, optimization), DLU (text document, text and image digital document). Finally, the "Electronic Banking and Information Security" group became the team "Monétique & Biometrics".